Sporadic and familial cases of aquagenic keratoderma

Kleine-Levin syndrome. Familial cases and comparison with sporadic cases.

OBJECTIVES To highlight the occurrence of familial cases and addresses, whether familial Kleine-Levine syndrome (KLS) presents the same spectrum of disease, as that seen in sporadic KLS.   METHODS Between September and December 2014, reports of familial cases of KLS were identified by searching the Library of Congress, PubMed, and Web of Science databases restricted to the English language, w...

Aquagenic Palmoplantar Keratoderma as a CFTR-related Disorder.

Crohn's disease severity in familial and sporadic cases.

BACKGROUND Having a relative with inflammatory bowel disease increases the risk for Crohn's disease but may also increase its severity in affected patients. AIMS To evaluate the influence of a family history on Crohn's disease course and severity. METHODS 1316 patients followed in the same unit were studied retrospectively. Age at onset, duration of illness, site, and extent of disease were...

Cervical dystonia: about familial and sporadic cases in 88 patients.

Cervical dystonia (CD) affects the musculature of the neck in a focal way or associated to other parts of the body. The aim of this study was to identify clinical differences between patients with dystonia patients without family history and with family history (sporadic). Eighty-eight patients with CD were recruited in a Movement Disorders Clinic between June of 2008 and June of 2009. Only pat...

Aquagenic Urticaria: A Report of Two Cases

Aquagenic urticaria is a rare form of physical urticaria, in which contact with water evokes wheals. A 19-year-old man and a 4-year-old boy complained of recurrent episodes of urticaria. Urticaria appeared while taking a bath or a shower, in the rain, or in a swimming pool. Well-defined pin head to small pea-sized wheals surrounded by variable sized erythema were provoked by contact with water ...